Oka Laila Kosam begins in the usual Tollywood manner – depicting a self-indulgent hero. In this case, it’s Karthik (Naga Chaitanya), the son of businessman Chandrakanth (Suman). Now, Nandana (Pooja Hegde) is the daughter of construction company owner Ramprasad (Shayaji Shinde). Karthik happens to see Nandana and falls in love at first sight. But a few misunderstandings crop up. In the meantime, Ramprasad fixes up the marriage of his daughter with a guy and Nandana decides to break her relationship with him. Who is that guy? Will misunderstandings get clear between Karthik – Nandu? Whether they get together or not, forms the rest of the storyline.
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